Insights from Dr. Ignacio Larrabide
Why It Matters
Understanding the long-term behavior of WEB devices is critical for improving patient care. These devices represent a significant advancement in treating wide-neck intracranial aneurysms, providing a minimally invasive option. However, accurately predicting their behavior over time remains a challenge that this study addresses by leveraging advanced imaging, morphology analysis, mechanics and CFD techniques.
These insights help physicians better predict how devices adapt within treated aneurysms, leading to more precise treatment planning and improved outcomes. They also offer actionable data for healthcare administrators to enhance efficiency and for device manufacturers to drive innovation.
A Conversation with Dr. Ignacio Larrabide: Advancing Precision in Aneurysm Treatment
Mentice: Dr. Larrabide, thank you for joining us today. Let's start with the basics—can you share the inspiration behind your study and its focus on WEB devices?
Dr. Ignacio Larrabide: Of course! The Woven EndoBridge, or WEB device, has been transformative for treating wide-neck intracranial aneurysms, offering a minimally invasive solution for patients. However, while the device has shown great promise, predicting its long-term behavior within aneurysms remains a significant clinical challenge. Our study was driven by the need to fill this gap and support physicians with a more precise understanding of how these devices behave over time.
Mentice: Your team introduced a pioneering 3D analysis methodology in this study. Can you explain what makes it unique?
Dr. Ignacio Larrabide: Certainly. We utilized 3DRA imaging alongside vascular morphology, device mechanics and CFD simulations to quantify changes in the WEB device. It includes parameters like its volume, surface area, and positional dynamics within treated aneurysms. What sets this apart is its ability to precisely measure and model these changes over time, offering previously unavailable insights.
Mentice: Why is understanding these changes so important for patient care?
Dr. Ignacio Larrabide: It's essential because how the device adapts within the aneurysm directly impacts the success of the treatment. By understanding these dynamics, physicians can make more informed decisions about device selection and treatment planning, which minimizes complications and enhances long-term outcomes. It's about moving toward truly personalized neurovascular care.
Mentice: How do you see these insights impacting neurovascular treatment and clinical practice?
Dr. Ignacio Larrabide: I believe this study sets the stage for a new era in precision medicine for aneurysm care. By bridging advanced computational techniques with clinical practice, we're empowering physicians with data-driven tools to improve decision-making. It also opens doors for device manufacturers to refine their designs, ensuring their products perform optimally over time.
Mentice: It sounds like this research has broad implications. Could you elaborate on its potential benefits for different stakeholders?
Dr. Ignacio Larrabide: Absolutely. It supports physicians with a clearer understanding of device behaviour, leading to better treatment planning and reduced risks. For healthcare administrators, it can improve efficiency by reducing retreatments and complications, translating to cost savings. For device manufacturers, it offers a roadmap for innovation and product development, strengthening market positioning with evidence-based credibility.
Mentice: That's exciting to hear. What's next for this research?
Dr. Ignacio Larrabide: We're excited to see how these insights are integrated into practical solutions. Mentice's Ankyras clinical decision-support application is a great example. It applies these findings to create better device sizing and selection tools, helping physicians optimize patient outcomes. It's collaborations like these that will advance the field.
Mentice: Thank you, Dr. Larrabide, for sharing your insights. This research highlights the importance of innovation and collaboration in advancing neurovascular care.
Dr. Ignacio Larrabide: Thank you! It's a privilege to contribute to a field that has such a direct impact on patient lives.
Broader Implications for Stakeholders
Driving Innovation in Post-Treatment Aneurysm Care with Ankyras
Mentice's research team is integrating these insights into the development of intrasaccular devices with Ankyras. This new approach introduces a fresh concept for device sizing, aiming not only to predict immediate device behavior but to provide a complete and accurate range of data for better device selection and improved patient outcomes.
Learn more about the study and Ankyras:
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About the Research Team
Dr. Ignacio Larrabide led this study in collaboration with Kevin Janot, Aymeric Rouchaud, and Ana Paula Narata, who collectively emphasized the transformative potential of this methodology to refine post-treatment care strategies and improve long-term patient outcomes.
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Contact Information
For more details about this study or to discuss collaborative opportunities, please contact:
Renan Cancissu, Director Precision Medicine, Mentice
E-post: renan.cancissu@mentice.com
Mobile: +34 637 892 019
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